380 research outputs found
APOGEE DR14/DR15 Abundances in the Inner Milky Way
We present an overview of the distributions of 11 elemental abundances in the
Milky Way's inner regions, as traced by APOGEE stars released as part of SDSS
Data Release 14/15 (DR14/DR15), including O, Mg, Si, Ca, Cr, Mn, Co, Ni, Na,
Al, and K. This sample spans ~4000 stars with R_GC<4 kpc, enabling the most
comprehensive study to date of these abundances and their variations within the
innermost few kiloparsecs of the Milky Way. We describe the observed abundance
patterns ([X/Fe]-[Fe/H]), compare to previous literature results and to
patterns in stars at the solar Galactic radius, and discuss possible trends
with DR14/DR15 effective temperatures. We find that the position of the
[Mg/Fe]-[Fe/H] "knee" is nearly constant with R_GC, indicating a well-mixed
star-forming medium or high levels of radial migration in the early inner
Galaxy. We quantify the linear correlation between pairs of elements in
different subsamples of stars and find that these relationships vary; some
abundance correlations are very similar between the alpha-rich and alpha-poor
stars, but others differ significantly, suggesting variations in the
metallicity dependencies of certain supernova yields. These empirical trends
will form the basis for more detailed future explorations and for the
refinement of model comparison metrics. That the inner Milky Way abundances
appear dominated by a single chemical evolutionary track and that they extend
to such high metallicities underscore the unique importance of this part of the
Galaxy for constraining the ingredients of chemical evolution modeling and for
improving our understanding of the evolution of the Galaxy as a whole.Comment: Submitted to AAS Journals; revised after referee repor
Estimating Heritabilities and Genetic Correlations: Comparing the âAnimal Modelâ with Parent-Offspring Regression Using Data from a Natural Population
Quantitative genetic parameters are nowadays more frequently estimated with restricted maximum likelihood using the âanimal modelâ than with traditional methods such as parent-offspring regressions. These methods have however rarely been evaluated using equivalent data sets. We compare heritabilities and genetic correlations from animal model and parent-offspring analyses, respectively, using data on eight morphological traits in the great reed warbler (Acrocephalus arundinaceus). Animal models were run using either mean trait values or individual repeated measurements to be able to separate between effects of including more extended pedigree information and effects of replicated sampling from the same individuals. We show that the inclusion of more pedigree information by the use of mean traits animal models had limited effect on the standard error and magnitude of heritabilities. In contrast, the use of repeated measures animal model generally had a positive effect on the sampling accuracy and resulted in lower heritabilities; the latter due to lower additive variance and higher phenotypic variance. For most trait combinations, both animal model methods gave genetic correlations that were lower than the parent-offspring estimates, whereas the standard errors were lower only for the mean traits animal model. We conclude that differences in heritabilities between the animal model and parent-offspring regressions were mostly due to the inclusion of individual replicates to the animal model rather than the inclusion of more extended pedigree information. Genetic correlations were, on the other hand, primarily affected by the inclusion of more pedigree information. This study is to our knowledge the most comprehensive empirical evaluation of the performance of the animal model in relation to parent-offspring regressions in a wild population. Our conclusions should be valuable for reconciliation of data obtained in earlier studies as well as for future meta-analyses utilizing estimates from both traditional methods and the animal model
Determinants of distribution and prevalence of avian malaria in blue tit populations across Europe : separating host and parasite effects
Although avian malarial parasites are globally distributed, the factors that affect the geographical distribution and local prevalence of different parasite lineages across host populations or species are still poorly understood. Based on the intense screening of avian malarial parasites in nine European blue tit populations, we studied whether distribution ranges as well as local adaptation, host specialization and phylogenetic relationships can determine the observed prevalences within populations. We found that prevalence differed consistently between parasite lineages and host populations, indicating that the transmission success of parasites is lineage specific but is partly shaped by locality-specific effects. We also found that the lineage-specific estimate of prevalence was related to the distribution range of parasites: lineages found in more host populations were generally more prevalent within these populations. Additionally, parasites with high prevalence that were also widely distributed among blue tit populations were also found to infect more host species. These findings suggest that parasites reaching high local prevalence can also realize wide distribution at a global scale that can have further consequences for host specialization. Although phylogenetic relationships among parasites did not predict prevalence, we detected a close match between a tree based on the geographic distance of the host populations and the parasite phylogenetic tree, implying that neighbouring host populations shared a related parasite fauna
Are bone erosions detected by magnetic resonance imaging and ultrasonography true erosions? A comparison with computed tomography in rheumatoid arthritis metacarpophalangeal joints
The objective of the study was, with multidetector computed tomography (CT) as the reference method, to determine whether bone erosions in rheumatoid arthritis (RA) metacarpophalangeal (MCP) joints detected with magnetic resonance imaging (MRI) and ultrasonography (US), but not with radiography, represent true erosive changes. We included 17 RA patients with at least one, previously detected, radiographically invisible MCP joint MRI erosion, and four healthy control individuals. They all underwent CT, MRI, US and radiography of the 2nd to 5th MCP joints of one hand on the same day. Each imaging modality was evaluated for the presence of bone erosions in each MCP joint quadrant. In total, 336 quadrants were examined. The sensitivity, specificity and accuracy, respectively, for detecting bone erosions (with CT as the reference method) were 19%, 100% and 81% for radiography; 68%, 96% and 89% for MRI; and 42%, 91% and 80% for US. When the 16 quadrants with radiographic erosions were excluded from the analysis, similar values for MRI (65%, 96% and 90%) and US (30%, 92% and 80%) were obtained. CT and MRI detected at least one erosion in all patients but none in control individuals. US detected at least one erosion in 15 patients, however, erosion-like changes were seen on US in all control individuals. Nine patients had no erosions on radiography. In conclusion, with CT as the reference method, MRI and US exhibited high specificities (96% and 91%, respectively) in detecting bone erosions in RA MCP joints, even in the radiographically non-erosive joints (96% and 92%). The moderate sensitivities indicate that even more erosions than are seen on MRI and, particularly, US are present. Radiography exhibited high specificity (100%) but low sensitivity (19%). The present study strongly indicates that bone erosions, detected with MRI and US in RA patients, represent a loss of calcified tissue with cortical destruction, and therefore can be considered true bone erosions
High-resolution, H band Spectroscopy of Be Stars with SDSS-III/APOGEE: I. New Be Stars, Line Identifications, and Line Profiles
APOGEE has amassed the largest ever collection of multi-epoch,
high-resolution (R~22,500), H-band spectra for B-type emission line (Be) stars.
The 128/238 APOGEE Be stars for which emission had never previously been
reported serve to increase the total number of known Be stars by ~6%. We focus
on identification of the H-band lines and analysis of the emission peak
velocity separations (v_p) and emission peak intensity ratios (V/R) of the
usually double-peaked H I and non-hydrogen emission lines. H I Br11 emission is
found to preferentially form in the circumstellar disks at an average distance
of ~2.2 stellar radii. Increasing v_p toward the weaker Br12--Br20 lines
suggests these lines are formed interior to Br11. By contrast, the observed IR
Fe II emission lines present evidence of having significantly larger formation
radii; distinctive phase lags between IR Fe II and H I Brackett emission lines
further supports that these species arise from different radii in Be disks.
Several emission lines have been identified for the first time including
~16895, a prominent feature in the spectra for almost a fifth of the sample
and, as inferred from relatively large v_p compared to the Br11-Br20, a tracer
of the inner regions of Be disks. Unlike the typical metallic lines observed
for Be stars in the optical, the H-band metallic lines, such as Fe II 16878,
never exhibit any evidence of shell absorption, even when the H I lines are
clearly shell-dominated. The first known example of a quasi-triple-peaked Br11
line profile is reported for HD 253659, one of several stars exhibiting intra-
and/or extra-species V/R and radial velocity variation within individual
spectra. Br11 profiles are presented for all discussed stars, as are full
APOGEE spectra for a portion of the sample.Comment: accepted in A
Target Selection for the Apache Point Observatory Galactic Evolution Experiment (APOGEE)
The Apache Point Observatory Galactic Evolution Experiment (APOGEE) is a
high-resolution infrared spectroscopic survey spanning all Galactic
environments (i.e., bulge, disk, and halo), with the principal goal of
constraining dynamical and chemical evolution models of the Milky Way. APOGEE
takes advantage of the reduced effects of extinction at infrared wavelengths to
observe the inner Galaxy and bulge at an unprecedented level of detail. The
survey's broad spatial and wavelength coverage enables users of APOGEE data to
address numerous Galactic structure and stellar populations issues. In this
paper we describe the APOGEE targeting scheme and document its various target
classes to provide the necessary background and reference information to
analyze samples of APOGEE data with awareness of the imposed selection criteria
and resulting sample properties. APOGEE's primary sample consists of ~100,000
red giant stars, selected to minimize observational biases in age and
metallicity. We present the methodology and considerations that drive the
selection of this sample and evaluate the accuracy, efficiency, and caveats of
the selection and sampling algorithms. We also describe additional target
classes that contribute to the APOGEE sample, including numerous ancillary
science programs, and we outline the targeting data that will be included in
the public data releases.Comment: Accepted to AJ. 31 pages, 11 figure
The Songbird Neurogenomics (SoNG) Initiative: Community-based tools and strategies for study of brain gene function and evolution
BACKGROUND: Songbirds hold great promise for biomedical, environmental and evolutionary research. A complete draft sequence of the zebra finch genome is imminent, yet a need remains for application of genomic resources within a research community traditionally focused on ethology and neurobiological methods. In response, we developed a core set of genomic tools and a novel collaborative strategy to probe gene expression in diverse songbird species and natural contexts. RESULTS: We end-sequenced cDNAs from zebra finch brain and incorporated additional sequences from community sources into a database of 86,784 high quality reads. These assembled into 31,658 non-redundant contigs and singletons, which we annotated via BLAST search of chicken and human databases. The results are publicly available in the ESTIMA:Songbird database. We produced a spotted cDNA microarray with 20,160 addresses representing 17,214 non-redundant products of an estimated 11,500â15,000 genes, validating it by analysis of immediate-early gene (zenk) gene activation following song exposure and by demonstrating effective cross hybridization to genomic DNAs of other songbird species in the Passerida Parvorder. Our assembly was also used in the design of the "Lund-zfa" Affymetrix array representing ~22,000 non-redundant sequences. When the two arrays were hybridized to cDNAs from the same set of male and female zebra finch brain samples, both arrays detected a common set of regulated transcripts with a Pearson correlation coefficient of 0.895. To stimulate use of these resources by the songbird research community and to maintain consistent technical standards, we devised a "Community Collaboration" mechanism whereby individual birdsong researchers develop experiments and provide tissues, but a single individual in the community is responsible for all RNA extractions, labelling and microarray hybridizations. CONCLUSION: Immediately, these results set the foundation for a coordinated set of 25 planned experiments by 16 research groups probing fundamental links between genome, brain, evolution and behavior in songbirds. Energetic application of genomic resources to research using songbirds should help illuminate how complex neural and behavioral traits emerge and evolve
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